PTEN Antibody (C30793) | Assay Biotech Inc.

PTEN Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C30793

Reactivity:Human,Mouse,Rat

Applications:IF,WB,IHC,ELISA

Modification:Unmodified/Total

Source:Polyclonal,Rabbit,IgG

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Tumor Suppressors/Apoptosis

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PTEN Antibody

Immunofluorescence analysis of human-heart tissue. 1,PTEN Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B

Delivery

Freight Charges

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

PTEN Antibody

Description

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency.The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. The use of a non-canonical (CUG) upstream initiation site produces a longer isoform that initiates translation with a leucine, and is thought to be preferentially associated with the mitochondrial inner membrane. This longer isoform may help regulate ener

Catalog No

C30793

Reactivity

Human, Mouse, Rat

Source

Polyclonal, Rabbit,IgG

Modification

Unmodified/Total

Applications

IF, WB, IHC, ELISA

Dilution

IF 1:50-200 IHC: 100-300.WB 1:500-2000, ELISA 1:10000-20000

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

phosphatase and tensin homolog; phosphatase and tensin homolog pseudogene 1

Molecular Weight (Da or kDa)

Gene Name

PTEN MMAC1 TEP1

Protein Name

PTEN

Human Gene ID

5728

Human Swiss Prot No.

P60484

Immunogen

Synthesized peptide derived from PTEN at AA range: 251-300

Specificity

PTEN Polyclonal Antibody detects endogenous levels of PTEN

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Catalog No: N1641

PTEN mouse Monoclonal Antibody(2C10)

Price/Quantity:
$160

Size:
50 ul

Catalog No: N1642

PTEN mouse Monoclonal Antibody(9E8)

Price/Quantity:
$160

Size:
50 ul

Publications (6)