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OAS2 Antibody

Catalog No : C30992
  • Reactivity
    Human,Rat,Mouse
  • Applications
    WB,IHC-p,IF(paraffin section),ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
Details
  • Product Name
    OAS2 Antibody
  • Description
    2'-5'-oligoadenylate synthetase 2(OAS2) Homo sapiens This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Catalog No
    C30992
  • Reactivity
    Human, Rat, Mouse
  • Applications
    WB, IHC-p, IF(paraffin section), ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Dilution
    Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/20000. Not yet tested in other applications.
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    OAS2; 2'-5'-oligoadenylate synthase 2; (2-5')oligo(A) synthase 2; 2-5A synthase 2; p69 OAS / p71 OAS; p69OAS / p71OAS
  • Molecular Weight (Da)
    82431
  • Gene Name
    OAS2
  • Protein Name
    2'-5'-oligoadenylate synthase 2
  • Human Gene ID
    4939
  • Human Swiss Prot No.
    P29728
  • Immunogen
    The antiserum was produced against synthesized peptide derived from the N-terminal region of human OAS2. AA range:61-110
  • Specificity
    OAS2 Polyclonal Antibody detects endogenous levels of OAS2 protein.
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.