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TGR5 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: G317
Reactivity:Human,Rat,Mouse
Applications:IF/ICC,ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
Product Details
Product Name
TGR5 Antibody
Description
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Catalog No
G317
Reactivity
Human, Rat, Mouse
Applications
IF/ICC, ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
GPBAR1; TGR5; G-protein coupled bile acid receptor 1; G-protein coupled receptor GPCR19; hGPCR19; Membrane-type receptor for bile acids; M-BAR; hBG37; BG37
Molecular Weight (Da)
35248
Gene Name
GPBAR1
Protein Name
G-protein coupled bile acid receptor 1
Human Gene ID
151306
Human Swiss Prot No.
Q8TDU6
Immunogen
The antiserum was produced against synthesized peptide derived from human GPBAR. AA range:11-60
Specificity
TGR5 Polyclonal Antibody detects endogenous levels of TGR5 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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