PIK3CA (H1047R) (AB1579) Mouse mAb (Ready to Use)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0111R

Species Reactivity:Human

Application:IHC

Host:Mouse

Clonality:Monoclonal

Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

Size:

Price/Quantity $70

Quantity:

Datasheet

SDS

Ready to Use Antibodies

Immunohistochemistry

PIK3CA (H1047R) (AB1579) Mouse mAb (Ready to Use)

Human colon tissue was stained with anti-TGF β Receptor I (AB1598) Antibody

Delivery

Freight Charges

Utilize our shipping calculator at checkout to view

Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

Promotions

Product Details

Product Name

PIK3CA (H1047R) (AB1579) Mouse mAb (Ready to Use)

Description

The PIK3CA gene is located at 3Q26. 3 and encodes a 124kDa protein. The protein is composed of 85kDa regulatory subunit and 110kDa catalytic subunit. The most common mutations of PIK3CA occur in exon 9 and exon 20. H1047R, one of the most common mutations occurs in exon 20. PIK3CA plays an important role in the PI3K/AKT/mTOR signaling pathway, which can be activated by this mutation, closely related to the occurrence of tumors and disease progression. In non-small cell lung cancer, H1047R mutantion can phosphorylate Akt and activate downstream pathways to promote the survival and expansion of tumor cells.

Catalog No

V0111R

Species Reactivity

Human

Clonality

Monoclonal

Host

Mouse

Modifcation

No Modification

Clone

AB1579

Isotype

IgG3, kappa

Application

IHC

Application Dilutions

It has been optimized for direct use, requiring no further dilution.

Immunogen

A synthetic peptide corresponding to the amino acid region 1000 - 1068 of the human PIK3CA protein.

Specificity

The antibody can specifically recognize humanPIK3CA H1047R protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Purification

Immunogen affinity purified

Subcellular Location

Cytoplasmic

Storage and Stability

Store at-20℃. Avoid freeze / thaw cycles.

Gene Name

PIK3CA

Gene ID

5290

Human swiss

P42336

Protein Name

PIK3CA H1047R

Synonyms

5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha, 5-bisphosphate 3-kinase catalytic subunit alpha isoform, caPI3K, CLOVE, CWS5, MCAP, MCM, MCMTC, MGC142161, MGC142163, p110 alpha, p110alpha, Phosphatidylinositol 3 kinase catalytic alpha polypeptide, Phosphatidylinositol 3 kinase catalytic 110 KD alpha, Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha, Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha isoform, Phosphatidylinositol 4, 5 bisphosphate 3 kinase 110 kDa catalytic subunit alpha, Phosphatidylinositol-4, Phosphoinositide 3 kinase catalytic alpha polypeptide, PI 3 Kinase catalytic subunit alpha, PI3 kinase p110 subunit alpha, PI3-kinase subunit alpha, PI3K, PI3K-alpha, PI3KC A, PIK3C A, Pik3ca, PK3CA, PK3CA_HUMAN, PtdIns 3 kinase p110, PtdIns-3-kinase subunit alpha, PtdIns-3-kinase subunit p110-alpha, Serine/threonine protein kinase PIK3CA