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Estrogen Receptor α (AB1445) Rabbit mAb (Ready to Use)
Estrogen Receptor α (AB1445) Rabbit mAb (Ready to Use)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M3768R
Species Reactivity:Human
Application:IHC
Host:Mouse
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$70
Product Details
Product Name
Estrogen Receptor α (AB1445) Rabbit mAb (Ready to Use)
Description
Estrogen receptor (ER) is a protein with 553 amino acids which belongs to the steroid receptor superfamily of nuclear receptors. It has three domains, including the central DNA- binding domain, the hormone- binding domain at the C- terminal, and the transcription- activating domain at the N- terminal. ER mediates regulatory functions of female sex steroids on growth, differentiation and function in several tissues, including female and male reproductive tract, mammary gland, and skeletal and cardiovascular systems. Clinical data show that ER in breast cancer is an important parameter for predicting the prognosis of breast cancer and endocrine therapy, so ER/PR is one of the routine examination items for breast cancer patients.
Catalog No
M3768R
Species Reactivity
Human
Clonality
Monoclonal
Host
Mouse
Modifcation
No Modification
Clone
AB1445
Isotype
IgG, Kappa
Application
IHC
Application Dilutions
It has been optimized for direct use, requiring no further dilution.
Immunogen
A synthetic peptide corresponding to the amino acid region 450 - 595 of the human Estrogen Receptor α protein.
Specificity
The antibody can recognize human Estrogen receptor protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Purification
Immunogen affinity purified
Subcellular Location
Nuclear
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene ID
2099
Human swiss
P03372
Protein Name
Estrogen Receptor α
Synonyms
ESR1 ESR NR3A1
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