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Primary Antibodies
CD117 (C-kit) (AB1294) Rabbit mAb (Ready to Use)
CD117 (C-kit) (AB1294) Rabbit mAb (Ready to Use)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M3720R
Species Reactivity:Human
Application:IHC
Host:Mouse
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$70
# Datasheet #
# SDS #
Ready to Use Antibodies
Immunohistochemistry
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CD117 (C-kit) (AB1294) Rabbit mAb (Ready to Use)

Human appendix was stained with anti-CD117 (C-kit) (AB1294) rabbit mAb

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Product Details
Product Name
CD117 (C-kit) (AB1294) Rabbit mAb (Ready to Use)
Description
CD117 is a cell membrane protein encoded by the c- kit proto- oncogene and is a type III transmembrane protein tyrosine kinase growth factor receptor. CD117 is expressed in mast cells, melanocytes and interstitial cells of Cajal. CD117 is positive in 80- 100% of gastric stromal sarcoma (GIST) . CD117, as a specific marker for immunohistochemical examination of gastric stromal sarcoma (GIST) , can be used to clinically guide the personalized target drug (Gleevec) treatment of GIST patients. CD117 can also be used to identify mast cell tumors in lymphoma and as a marker for some testicular germ cell tumors.
Catalog No
M3720R
Species Reactivity
Human
Clonality
Monoclonal
Host
Mouse
Modifcation
No Modification
Clone
AB1294
Isotype
IgG, Kappa
Application
IHC
Application Dilutions
It has been optimized for direct use, requiring no further dilution.
Immunogen
A synthetic peptide corresponding to the amino acid region 1 - 100 of the human CD117 protein.
Specificity
The antibody can specifically recognize human CD117 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Purification
Immunogen affinity purified
Subcellular Location
Cytoplasmic, Membranous
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
KIT
Gene ID
3815
Human swiss
P10721
Protein Name
CD117
Synonyms
C Kit；c-Kit；c-Kit Ligand；CD117；Kit；Kit Ligand；KIT oncogene；KIT proto oncogene receptor tyrosine kinase；KIT_HUMAN；Mast cell growth factor receptor；Mast/stem cell growth factor receptor Kit；MGF；p145 c-kit；PBT；Piebald trait protein；Proto oncogene c Kit；Proto oncogene tyrosine protein kinase Kit；Proto-oncogene c-Kit；SCF Receptor；SCFR；soluble KIT variant 1；Steel Factor Receptor；Stem cell factor receptor；tyrosine protein kinase Kit；Tyrosine-protein kinase Kit；v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog；v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein；v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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