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E-Cadherin (AB1337) Mouse mAb (Ready to Use)
E-Cadherin (AB1337) Mouse mAb (Ready to Use)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0519R
Species Reactivity:Human,Mouse,Rat
Application:Immunohistochemistry (IHC)
Host:Mouse
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$70
# Datasheet #
# SDS #
Ready to Use Antibodies
Immunohistochemistry
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E-Cadherin (AB1337) Mouse mAb (Ready to Use)

Human cerxiv tissue was stained with anti-Cytokeratin 5/6 (AB1529) Antibody

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Product Details
Product Name
E-Cadherin (AB1337) Mouse mAb (Ready to Use)
Description
E- Cadherein, 120kDa, is a critical regulator of epithelial junction formation. The E- cadherin internal domain binds with alpha, beta, gamma, and p120 catenins to anchor the ECAD complex to the actin cytoskeleton of the cell. E- cadherin is expressed in virtually all epithelial cells with the exception of adrenocortical cells. The expression in liver cells is weaker than in most other epithelia. ECAD is also expressed in melanocytes (adhering to squamous epithelial cells) . Mesothelial cells and granulosa cells are ECAD negative. Mesenchymal cells and neural crest cells are mostly negative but some types may show a weak reaction. Testicular germinative cells are weakly positive. At present, it is commonly used to differentiate breast lobular cancer from ductal cancer (the former is often negative, the latter is often positive) .
Catalog No
V0519R
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Mouse
Modifcation
No Modification
Clone
AB1337
Isotype
IgG2b, kappa
Application
Immunohistochemistry (IHC)
Application Dilutions
It has been optimized for direct use, requiring no further dilution.
Immunogen
A synthetic peptide corresponding to the amino acid region 700 - 800 of the human E - Cadherin protein.
Specificity
The antibody can specifically recognize E- cadherin protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Purification
Immunogen affinity purified
Subcellular Location
Membranous
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
CDH1
Gene ID
999
Human swiss
P12830
Protein Name
E-Cadherin
Synonyms
Cadherin-1, CAM 120/80, Epithelial cadherin (E-cadherin) , Uvomorulin, CD324, CDH1, CDHE
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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