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Cytokeratin 8 (AB1459) Mouse mAb (Ready to Use)
Cytokeratin 8 (AB1459) Mouse mAb (Ready to Use)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0494R
Species Reactivity:Human,Mouse,Rat
Application:Immunohistochemistry (IHC)
Host:Mouse
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$70
Product Details
Product Name
Cytokeratin 8 (AB1459) Mouse mAb (Ready to Use)
Description
Cytokeratin 8 (CK8) is a member of the type II family of cytokeratins with a molecular weight of 53kDa which plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. It generally exists in monolayer and pseudostratified epithelium, and is expressed in glandular epithelium, transitional epithelium and hepatocytes. It is absent in squamous cell carcinomas. CK8 dimerizes with CK18 to form an intermediate filament in simple single- layered epithelial cells. CK8/18 expression patterns are useful for classification of tumors of unknown origin and poorly differentiated carcinomas.
Catalog No
V0494R
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Mouse
Modifcation
No Modification
Clone
AB1459
Isotype
IgG2b, kappa
Application
Immunohistochemistry (IHC)
Application Dilutions
It has been optimized for direct use, requiring no further dilution.
Immunogen
A synthetic peptide corresponding to the amino acid region 400 - 483 of the human Cytokeratin 8 protein.
Specificity
The antibody can specifically recognize human CK8 protein, and shows no cross reaction with CK1, 4, 5, 6, 7, 10, 15, 16, 17, 18, 20.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Purification
Immunogen affinity purified
Subcellular Location
Cytoplasmic, Membranous
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
KRT8 CYK8
Gene ID
3856
Human swiss
P05787
Protein Name
Cytokeratin 8
Synonyms
CARD2, CK 8, CK-8, CK8, CYK8, CYKER, Cytokeratin endo A, Cytokeratin-8, DreK8, EndoA, K2C8, K2C8_HUMAN, K8, Keratin 8, Keratin type II cytoskeletal 8, Keratin, type II cytoskeletal 8, Keratin-8, KO, Krt 2. 8, KRT8, MGC118110, MGC174782, MGC53564, MGC85764, sb:cb186, Type-II keratin Kb8
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