eIF2α (Phospho Ser51) (AB2377) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: WP1877

Species Reactivity:Human; Mouse; Rat;

Application:WB; IF; ELISA

Host:Mouse

Clonality:Monoclonal

Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

Size:

Price/Quantity $135

Quantity:

Datasheet

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eIF2α (Phospho Ser51) (AB2377) mouse mAb

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

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Product Details

Product Name

eIF2α (Phospho Ser51) (AB2377) mouse mAb

Description

The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1) , the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908) , and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161) . The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al. , 1987 [PubMed 2948954]) . [supplied by OMIM, Feb 2010],

Catalog No

WP1877

Species Reactivity

Human; Mouse; Rat;

Clonality

Monoclonal

Host

Mouse

Modifcation

Phospho S51

Clone

AB2377

Isotype

IgG2b, kappa

Application

WB; IF; ELISA

Application Dilutions

WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.

Immunogen

A synthesized phosphopeptide corresponding to residues surrounding Ser51 of human eIF2α.

Specificity

This antibody detects endogenous levels of eIF2α (Phospho Ser51) protein.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Purification

The antibody was purified by protein G affinity chromatography.

Storage and Stability

Store at-20℃. Avoid freeze / thaw cycles.

Gene Name

EIF2S1

Gene ID

1965

Human swiss

P05198

Protein Name

eIF2α

Synonyms

Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha (eIF-2-alpha, eIF-2A, eIF-2alpha, eIF2-alpha) , EIF2S1, EIF2A