PI3 Kinase p85 (Phospho Tyr458)/p55 (Phospho Tyr199) (AB5383) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M4074

Species Reactivity:Human

Application:WB,IHC,IF,ELISA

Host:Rabbit

Clonality:Monoclonal

Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

Size:

Price/Quantity $135

Quantity:

Datasheet

SDS

Recombinant Antibody

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PI3 Kinase p85 (Phospho Tyr458)/p55 (Phospho Tyr199) (AB5383) Rabbit mAb

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

PI3 Kinase p85 (Phospho Tyr458)/p55 (Phospho Tyr199) (AB5383) Rabbit mAb

Description

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011],

Catalog No

M4074

Species Reactivity

Human

Clonality

Monoclonal

Host

Rabbit

Modifcation

Phospho Tyr458 / Phospho Tyr199

Clone

AB5383

Isotype

IgG

Application

WB, IHC, IF, ELISA

Application Dilutions

WB, 1:1000-1:2000 | IHC-P, 1:100-1:400 | IF/ICC, 1:100-1:400 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Immunogen

Recombinant protein (or fragment). This information is considered to be commercially sensitive.

Specificity

The antibody detects endogenous levels of PI3 Kinase p85 protein when phosphorylated at Tyr458 and p55 protein when phosphorylated at Tyr199. The antibody does not cross-react with PI3 Kinase p85/p55 phosphorylated at other sites.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Purification

The antibody was purified by protein A affinity chromatography.

Storage and Stability

Store at-20℃. Avoid freeze / thaw cycles.

Gene Name

PIK3R1

Gene ID

5295

Human swiss

P27986; Q92569; O00459

Protein Name

PI3 Kinase p85 (Phospho Tyr458)/p55 (Phospho Tyr199)

Synonyms

PIK3R1, GRB1, Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha