p70 S6 Kinase (Phospho Thr389) (AB5380) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M4071

Species Reactivity:Human

Application:WB,IHC,IF,ELISA

Host:Rabbit

Clonality:Monoclonal

Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

Size:

Price/Quantity $135

Quantity:

Datasheet

SDS

Recombinant Antibody

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p70 S6 Kinase (Phospho Thr389) (AB5380) Rabbit mAb

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0145

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Product Details

Product Name

p70 S6 Kinase (Phospho Thr389) (AB5380) Rabbit mAb

Description

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Catalog No

M4071

Species Reactivity

Human

Clonality

Monoclonal

Host

Rabbit

Modifcation

Phospho Thr389

Clone

AB5380

Isotype

IgG

Application

WB, IHC, IF, ELISA

Application Dilutions

WB, 1:1000-1:2000 | IHC-P, 1:100-1:400 | IF/ICC, 1:100-1:400 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Immunogen

Recombinant protein (or fragment). This information is considered to be commercially sensitive.

Specificity

The antibody detects endogenous levels of p70 S6 Kinase protein only when phosphorylated at Thr389. The antibody does not cross-react with p70 S6 Kinase phosphorylated at other sites.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Purification

The antibody was purified by protein A affinity chromatography.

Storage and Stability

Store at-20℃. Avoid freeze / thaw cycles.

Gene Name

KS6B1

Gene ID

6198

Human swiss

P23443

Protein Name

p70 S6 Kinase (Phospho Thr389)

Synonyms

Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)