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Primary Antibodies
IRF3 (Phospho Ser386) (AB5355) Rabbit mAb
IRF3 (Phospho Ser386) (AB5355) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M4046
Species Reactivity:Human
Application:WB,IHC,IF,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$135
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Recombinant Antibody
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IRF3 (Phospho Ser386) (AB5355) Rabbit mAb

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Product Details
Product Name
IRF3 (Phospho Ser386) (AB5355) Rabbit mAb
Description
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7.
Catalog No
M4046
Species Reactivity
Human
Clonality
Monoclonal
Host
Rabbit
Modifcation
Phospho Ser386
Clone
AB5355
Isotype
IgG
Application
WB, IHC, IF, ELISA
Application Dilutions
WB, 1:1000-1:2000 | IHC-P, 1:100-1:400 | IF/ICC, 1:100-1:400 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
Recombinant protein (or fragment). This information is considered to be commercially sensitive.
Specificity
The antibody detects endogenous levels of IRF3 protein only when phosphorylated at Ser386. The antibody does not cross-react with IRF3 phosphorylated at other sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
IRF3
Gene ID
3661
Human swiss
Q14653
Protein Name
IRF3 (Phospho Ser386)
Synonyms
Interferon regulatory factor 3 (IRF-3)
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