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APOB (AB2646) Rabbit mAb
APOB (AB2646) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2791
Species Reactivity:Human,Mouse,Rat
Application:IF/ICC,IHC-P,ELISA
Host:Rabbit
Clonality:Monoclonal Antibodies
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
Product Details
Product Name
APOB (AB2646) Rabbit mAb
Description
This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins (LDL) , and is the ligand for the LDL receptor. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA) , resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
Catalog No
M2791
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal Antibodies
Host
Rabbit
Modifcation
Unmodified
Clone
AB2646
Isotype
IgG
Application
IF/ICC, IHC-P, ELISA
Application Dilutions
IF/ICC, 1:200-1:400 | IHC-P, 1:500-1:5000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
Recombinant protein (or fragment). This information is considered to be commercially sensitive.
Specificity
This antibody detects endogenous levels of APOB protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% proclin300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
APOB
Gene ID
338
Human swiss
P04114
Protein Name
APOB
Synonyms
FLDB; FCHL2; LDLCQ4; apoB-48; apoB-100
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