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4E-BP1 (Phospho Thr37/46) (AB2302) Rabbit mAb
4E-BP1 (Phospho Thr37/46) (AB2302) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M3604
Species Reactivity:Human,Mouse,Rat
Application:WB;IF;IP;ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$135
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Recombinant Antibody
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4E-BP1 (Phospho Thr37/46) (AB2302) Rabbit mAb

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Product Details
Product Name
4E-BP1 (Phospho Thr37/46) (AB2302) Rabbit mAb
Description
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) , which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]
Catalog No
M3604
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
phospho T37/46
Clone
AB2302
Isotype
IgG
Application
WB;IF;IP;ELISA
Application Dilutions
WB, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
Recombinant protein (or fragment). This information is considered to be commercially sensitive.
Specificity
The antibody detects endogenous levels of 4E-BP1 protein only when phosphorylated at Thr37and Thr46. The antibody does not cross-react with 4E-BP1 phosphorylated at other sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
EIF4EBP1
Gene ID
1978
Human swiss
Q13541
Protein Name
Eukaryotic translation initiation factor 4E-binding protein 1
Synonyms
EIF4EBP1;Eukaryotic translation initiation factor 4E-binding protein 1;4E-BP1;eIF4E-binding protein 1;Phosphorylated heat-and acid-stable protein regulated by insulin 1;PHAS-I
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