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β Catenin (Phospho Thr41/Ser45) (AB2100) Rabbit mAb
β Catenin (Phospho Thr41/Ser45) (AB2100) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M3433
Species Reactivity:Human,Mouse,Rat,
Application:WB,IF,IP,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$135
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Recombinant Antibody
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β Catenin (Phospho Thr41/Ser45) (AB2100) Rabbit mAb

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Product Details
Product Name
β Catenin (Phospho Thr41/Ser45) (AB2100) Rabbit mAb
Description
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs) . AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC) , pilomatrixoma (PTR) , medulloblastoma (MDB) , and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016],
Catalog No
M3433
Species Reactivity
Human, Mouse, Rat,
Clonality
Monoclonal
Host
Rabbit
Modifcation
phospho T41 / S45
Clone
AB2100
Isotype
IgG
Application
WB, IF, IP, ELISA
Application Dilutions
WB, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
Recombinant protein (or fragment). This information is considered to be commercially sensitive.
Specificity
The antibody detects endogenous levels of β Catenin protein only when phosphorylated at Thr41 and Ser45. The antibody does not cross-react with β Catenin phosphorylated at other sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
CTNNB1 CTNNB OK/SW-cl. 35 PRO2286
Gene ID
1499
Human swiss
P35222
Protein Name
β Catenin (Phospho Thr41/Ser45)
Synonyms
CTNNB1, CTNNB, OK/SW-cl. 35, Catenin beta-1, Beta-catenin
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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