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GCLC (AB2075) Rabbit mAb
GCLC (AB2075) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M3407
Species Reactivity:Human,Mouse,Rat,
Application:WB,IF,IP,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$135
Product Details
Product Name
GCLC (AB2075) Rabbit mAb
Description
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction. [provided by RefSeq, Oct 2010],
Catalog No
M3407
Species Reactivity
Human, Mouse, Rat,
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB2075
Isotype
IgG
Application
WB, IF, IP, ELISA
Application Dilutions
WB, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
Recombinant protein (or fragment). This information is considered to be commercially sensitive.
Specificity
This antibody detects endogenous levels of GCLC protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
GCLC
Gene ID
2729
Human swiss
P48506
Protein Name
GCLC
Synonyms
GCLC, GLCL, GLCLC, Glutamate-- cysteine ligase catalytic subunit, GCS heavy chain, Gamma-ECS, Gamma-glutamylcysteine synthetase
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