xCT (AB1905) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M3234

Species Reactivity:Human,Mouse,Rat,

Application:WB,IHC,IF,IP,ELISA

Host:Rabbit

Clonality:Monoclonal

Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

Size:

Price/Quantity $135

Quantity:

Datasheet

SDS

Recombinant Antibody

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xCT (AB1905) Rabbit mAb

Delivery

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

xCT (AB1905) Rabbit mAb

Description

This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc (-) , the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]

Catalog No

M3234

Species Reactivity

Human, Mouse, Rat,

Clonality

Monoclonal

Host

Rabbit

Modifcation

Unmodified

Clone

AB1905

Isotype

IgG

Application

WB, IHC, IF, IP, ELISA

Application Dilutions

WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.

Immunogen

Recombinant protein (or fragment). This information is considered to be commercially sensitive.

Specificity

This antibody detects endogenous levels of xCT protein.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Purification

The antibody was purified by protein A affinity chromatography.

Storage and Stability

Store at-20℃. Avoid freeze / thaw cycles.

Gene Name

SLC7A11

Gene ID

23657

Human swiss

Q9UPY5

Protein Name

xCT

Synonyms

Cystine/glutamate transporter (Amino acid transport system xc-) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT)