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Histone H2A.X (phospho Ser139) (AB1859) Rabbit mAb
Histone H2A.X (phospho Ser139) (AB1859) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M3189
Species Reactivity:Human,Mouse,Rat,
Application:WB,IHC,IF,IP,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$135
Product Details
Product Name
Histone H2A.X (phospho Ser139) (AB1859) Rabbit mAb
Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],
Catalog No
M3189
Species Reactivity
Human, Mouse, Rat,
Clonality
Monoclonal
Host
Rabbit
Modifcation
phospho S139
Clone
AB1859
Isotype
IgG
Application
WB, IHC, IF, IP, ELISA
Application Dilutions
WB, 1:1000-1:5000 | IHC, 1:2000-1:8000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
Recombinant protein (or fragment). This information is considered to be commercially sensitive.
Specificity
The antibody detects endogenous levels of Histone H2A. X protein only when phosphorylated at Ser139. The antibody does not cross-react with Histone H2A. X phosphorylated at other sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
H2AFX
Gene ID
3014
Human swiss
P16104
Protein Name
Histone H2A. X (phospho Ser139)
Synonyms
H2AFX, H2AX, Histone H2A. x, H2a/x
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