25% Off Select Antibodies and ELISA Kits
Sign In/Register 0

We use cookies, check our Privacy Policies.

Bad (AB1784) Rabbit mAb
Bad (AB1784) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M3134
Species Reactivity:Human,Mouse,Rat,
Application:WB,IHC,IF,IP,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$135
Product Details
Product Name
Bad (AB1784) Rabbit mAb
Description
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008],
Catalog No
M3134
Species Reactivity
Human, Mouse, Rat,
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB1784
Isotype
IgG
Application
WB, IHC, IF, IP, ELISA
Application Dilutions
WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
Recombinant protein (or fragment). This information is considered to be commercially sensitive.
Specificity
This antibody detects endogenous levels of Bad protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
>>EGFR tyrosine kinase inhibitor resistance, >>Endocrine resistance, >>Platinum drug resistance, >>ErbB signaling pathway, >>Ras signaling pathway, >>cGMP-PKG signaling pathway, >>cAMP signaling pathway, >>Chemokine signaling pathway, >>Autophagy-animal, >>PI3K-Akt signaling pathway, >>Apoptosis, >>VEGF signaling pathway, >>Focal adhesion, >>Neurotrophin signaling pathway, >>Insulin signaling pathway, >>Thyroid hormone signaling pathway, >>Alzheimer disease, >>Amyotrophic lateral sclerosis, >>Prion disease, >>Pathways of neurodegeneration-multiple diseases, >>Toxoplasmosis, >>Tuberculosis, >>Hepatitis C, >>Hepatitis B, >>Measles, >>Human papillomavirus infection, >>Herpes simplex virus 1 infection, >>Human immunodeficiency virus 1 infection, >>Pathways in cancer, >>Viral carcinogenesis, >>Chemical carcinogenesis-receptor activation, >>Chemical carcinogenesis-reactive oxygen species, >>Colorectal cancer, >>Renal cell carcinoma, >>Pancreatic cancer, >>Endometrial cancer, >>Prostate cancer, >>Melanoma, >>Chronic myeloid leukemia, >>Acute myeloid leukemia, >>Non-small cell lung cancer, >>Hepatocellular carcinoma, >>Lipid and atherosclerosis
Gene ID
572
Human swiss
Q92934
Protein Name
Bad
Synonyms
BAD, BBC6, BCL2L8, Bcl2 antagonist of cell death, BAD, Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl2-L-8, Bcl-XL/Bcl-2-associated death promoter
Related Products