S6K1 (AB1683) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M3050

Species Reactivity:Human,Mouse,Rat,

Application:WB,IHC,IF,IP,ELISA

Host:Rabbit

Clonality:Monoclonal

Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

Size:

Price/Quantity $135

Quantity:

Datasheet

SDS

Recombinant Antibody

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S6K1 (AB1683) Rabbit mAb

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

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Product Details

Product Name

S6K1 (AB1683) Rabbit mAb

Description

ribosomal protein S6 kinase B1 (RPS6KB1) Homo sapiens This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013],

Catalog No

M3050

Species Reactivity

Human, Mouse, Rat,

Clonality

Monoclonal

Host

Rabbit

Modifcation

Unmodified

Clone

AB1683

Isotype

IgG

Application

WB, IHC, IF, IP, ELISA

Application Dilutions

WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.

Immunogen

Recombinant protein (or fragment). This information is considered to be commercially sensitive.

Specificity

This antibody detects endogenous levels of S6K1 protein.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Purification

The antibody was purified by protein A affinity chromatography.

Storage and Stability

Store at-20℃. Avoid freeze / thaw cycles.

Gene Name

>>EGFR tyrosine kinase inhibitor resistance, >>Endocrine resistance, >>ErbB signaling pathway, >>HIF-1 signaling pathway, >>Autophagy-animal, >>mTOR signaling pathway, >>PI3K-Akt signaling pathway, >>AMPK signaling pathway, >>Longevity regulating pathway, >>Longevity regulating pathway-multiple species, >>TGF-beta signaling pathway, >>Apelin signaling pathway, >>Fc gamma R-mediated phagocytosis, >>Thermogenesis, >>Insulin signaling pathway, >>Insulin resistance, >>Shigellosis, >>Human cytomegalovirus infection, >>Human papillomavirus infection, >>Human immunodeficiency virus 1 infection, >>Pathways in cancer, >>Proteoglycans in cancer, >>Chemical carcinogenesis-receptor activation, >>Colorectal cancer, >>Pancreatic cancer, >>Acute myeloid leukemia, >>Breast cancer, >>Hepatocellular carcinoma, >>Gastric cancer, >>Choline metabolism in cancer, >>PD-L1 expression and PD-1 checkpoint pathway in cancer

Gene ID

6198

Human swiss

P23443

Protein Name

S6K1

Synonyms

RPS6KB1, STK14A, Ribosomal protein S6 kinase beta-1, S6K-beta-1, S6K1, 70 kDa ribosomal protein S6 kinase 1, P70S6K1, p70-S6K 1, Ribosomal protein S6 kinase I, Serine/threonine-protein kinase 14A, p70 ribosomal S6 kinase alpha, p70 S6 kinas