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Primary Antibodies
ErbB4/HER4 (Phospho Tyr1284) (AB3423) Rabbit mAb
ErbB4/HER4 (Phospho Tyr1284) (AB3423) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2768
Species Reactivity:Human
Application:WB,IF/ICC,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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ErbB4/HER4 (Phospho Tyr1284) (AB3423) Rabbit mAb

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Product Details
Product Name
ErbB4/HER4 (Phospho Tyr1284) (AB3423) Rabbit mAb
Description
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Catalog No
M2768
Species Reactivity
Human
Clonality
Monoclonal
Host
Rabbit
Modifcation
Phospho Y1284
Clone
AB3423
Isotype
IgG
Application
WB, IF/ICC, ELISA
Application Dilutions
WB, 1:500-1:1000 | IF/ICC, 1:50-1:200 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic phosphorylated peptide around Y1284 of human ErbB4/HER4.
Specificity
The antibody detects endogenous levels of ErbB4/HER4 protein only when phosphorylated at Tyr1284. The antibody does not cross-react with ErbB4/HER4 phosphorylated at other sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.09% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
ERBB4
Gene ID
2066
Human swiss
Q15303
Protein Name
ErbB4/HER4 (Phospho Tyr1284)
Synonyms
HER4; ALS19; p180erbB4
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Primary Antibodies

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