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HSP27/HSPB1(Phospho Ser15) (AB3818) Rabbit mAb
HSP27/HSPB1(Phospho Ser15) (AB3818) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2765
Species Reactivity:Human
Application:WB,IF/ICC,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
Product Details
Product Name
HSP27/HSPB1(Phospho Ser15) (AB3818) Rabbit mAb
Description
This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.
Catalog No
M2765
Species Reactivity
Human
Clonality
Monoclonal
Host
Rabbit
Modifcation
Phospho S15
Clone
AB3818
Isotype
IgG
Application
WB, IF/ICC, ELISA
Application Dilutions
WB, 1:1000-1:5000 | IF/ICC, 1:50-1:200 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic phosphorylated peptide around S15 of human - HSP27/HSPB1.
Specificity
The antibody detects endogenous levels of HSP27/HSPB1 protein only when phosphorylated at Ser15. The antibody does not cross-react with HSP27/HSPB1 phosphorylated at other sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% proclin300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
HSPB1
Gene ID
3315
Human swiss
P04792
Protein Name
HSP27/HSPB1(Phospho Ser15)
Synonyms
CMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS. 76067; HEL-S-102; Phospho-HSP27/HSPB1-S15
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