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PLC gamma 1 (PLCG1) (Phospho Ser1248) (AB4577) Rabbit mAb
PLC gamma 1 (PLCG1) (Phospho Ser1248) (AB4577) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2756
Species Reactivity:Human,Mouse
Application:WB,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
# Datasheet #
# SDS #
Recombinant Antibody
20 ul Size Available
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PLC gamma 1 (PLCG1) (Phospho Ser1248) (AB4577) Rabbit mAb

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Product Details
Product Name
PLC gamma 1 (PLCG1) (Phospho Ser1248) (AB4577) Rabbit mAb
Description
The protein encoded by this gene catalyzes the formation of inositol 1, 4, 5-trisphosphate and diacylglycerol from phosphatidylinositol 4, 5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
Catalog No
M2756
Species Reactivity
Human, Mouse
Clonality
Monoclonal
Host
Rabbit
Modifcation
Phospho S1248
Clone
AB4577
Isotype
IgG
Application
WB, ELISA
Application Dilutions
WB, 1:1000-1:5000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic phosphorylated peptide around S1248 of human PLC gamma 1.
Specificity
The antibody detects endogenous levels of PLC gamma 1 protein only when phosphorylated at Ser1248. The antibody does not cross-react with PLC gamma 1 phosphorylated at other sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.09% Sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
PLCG1
Gene ID
5335
Human swiss
P19174
Protein Name
PLC gamma 1 (PLCG1) (Phospho Ser1248)
Synonyms
PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1
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