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GSK3β (Phospho Tyr216) + GSK3α (Phospho Tyr279) (AB3665) Rabbit mAb
GSK3β (Phospho Tyr216) + GSK3α (Phospho Tyr279) (AB3665) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2752
Species Reactivity:Mouse
Application:WB,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
Product Details
Product Name
GSK3β (Phospho Tyr216) + GSK3α (Phospho Tyr279) (AB3665) Rabbit mAb
Description
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Catalog No
M2752
Species Reactivity
Mouse
Clonality
Monoclonal
Host
Rabbit
Modifcation
Phospho Y216/Y279
Clone
AB3665
Isotype
IgG
Application
WB, ELISA
Application Dilutions
WB, 1:1000-1:4000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic phosphorylated peptide around Y216&Y279 of human GSK3β/GSK3α.
Specificity
The antibody detects endogenous levels of GSK3β protein only when phosphorylated at Tyr216 and GSK3α protein phosphorylated at Tyr279. The antibody does not cross-react with GSK3β and GSK3α phosphorylated at other sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.09% Sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
GSK3A/GSK3B
Gene ID
2931; 2932
Human swiss
P49840; P49841
Protein Name
GSK3β (Phospho Tyr216) + GSK3α (Phospho Tyr279)
Synonyms
GSK3B; GSK 3 beta; GSK3A; GSK 3 alpha; Phospho-GSK3α-S21+GSK3β-S9
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