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Primary Antibodies
PLC gamma 2 (PLCG2) (Phospho Tyr759) (AB4580) Rabbit mAb
PLC gamma 2 (PLCG2) (Phospho Tyr759) (AB4580) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2751
Species Reactivity:Human
Application:WB,IF/ICC,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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PLC gamma 2 (PLCG2) (Phospho Tyr759) (AB4580) Rabbit mAb

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Product Details
Product Name
PLC gamma 2 (PLCG2) (Phospho Tyr759) (AB4580) Rabbit mAb
Description
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4, 5-bisphosphate to 1D-myo-inositol 1, 4, 5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
Catalog No
M2751
Species Reactivity
Human
Clonality
Monoclonal
Host
Rabbit
Modifcation
Phospho Y759
Clone
AB4580
Isotype
IgG
Application
WB, IF/ICC, ELISA
Application Dilutions
WB, 1:2000-1:6000 | IF/ICC, 1:50-1:200 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic phosphorylated peptide around Y759 of human PLC gamma 2.
Specificity
The antibody detects endogenous levels of PLC gamma 2 protein only when phosphorylated at Tyr759. The antibody does not cross-react with PLC gamma 2 phosphorylated at other sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% proclin300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
PLCG2
Gene ID
5336
Human swiss
P16885
Protein Name
PLC gamma 2 (PLCG2) (Phospho Tyr759)
Synonyms
FCAS3; APLAID; PLC-IV; PLC-gamma-2; Phospho-PLC gamma 2 (PLCG2)-Y759
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