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Primary Antibodies
RB(Phospho Ser780) (AB4739) Rabbit mAb
RB(Phospho Ser780) (AB4739) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2746
Species Reactivity:Mouse,Rat
Application:WB,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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RB(Phospho Ser780) (AB4739) Rabbit mAb

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Product Details
Product Name
RB(Phospho Ser780) (AB4739) Rabbit mAb
Description
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB) , bladder cancer, and osteogenic sarcoma.
Catalog No
M2746
Species Reactivity
Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Phospho S780
Clone
AB4739
Isotype
IgG
Application
WB, ELISA
Application Dilutions
WB, 1:2000-1:10000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic phosphorylated peptide around S780 of mouse Phospho - RB - S780.
Specificity
The antibody detects endogenous levels of RB protein only when phosphorylated at Ser780. The antibody does not cross-react with RB phosphorylated at other sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.09% Sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
RB1
Gene ID
5925
Human swiss
P06400
Protein Name
RB(Phospho Ser780)
Synonyms
RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; p110-RB1; Phospho-RB-S780
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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