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Primary Antibodies
Flt3/CD135 (AB3513) Rabbit mAb
Flt3/CD135 (AB3513) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2658
Species Reactivity:Human,Mouse,Rat
Application:IHC-P,FC,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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Flt3/CD135 (AB3513) Rabbit mAb

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Product Details
Product Name
Flt3/CD135 (AB3513) Rabbit mAb
Description
This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
Catalog No
M2658
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB3513
Isotype
IgG
Application
IHC-P, FC, ELISA
Application Dilutions
IHC-P, 1:50-1:200 | FC, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 27 - 163 of human Flt3/CD135.
Specificity
This antibody detects endogenous levels of Flt3/CD135 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% proclin300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
FLT3
Gene ID
2322
Human swiss
P36888
Protein Name
Flt3/CD135
Synonyms
FLK2; STK1; CD135; FLK-2; Flt3/CD135
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