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Histone H3 (Di Methyl Lys79) (AB3740) Rabbit mAb
Histone H3 (Di Methyl Lys79) (AB3740) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2427
Species Reactivity:Human,Mouse,Rat,Other (Wide Range Predicted)
Application:WB,DB,ELISA,ChIP,ChIP-seq
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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Histone H3 (Di Methyl Lys79) (AB3740) Rabbit mAb

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Product Details
Product Name
Histone H3 (Di Methyl Lys79) (AB3740) Rabbit mAb
Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21. 3.
Catalog No
M2427
Species Reactivity
Human, Mouse, Rat, Other (Wide Range Predicted)
Clonality
Monoclonal
Host
Rabbit
Modifcation
DiMethyl K79
Clone
AB3740
Isotype
IgG
Application
WB, DB, ELISA, ChIP, ChIP-seq
Application Dilutions
WB, 1:1000-1:5000 | DB, 1:1000-1:5000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. | ChIP, 5μg antibody for 5μg-10μg of Chromatin | ChIP-seq, 1:50-1:200
Immunogen
A synthetic dimethylated peptide around K79 of human Histone H3 - K79.
Specificity
The antibody detects endogenous levels of Histone H3 protein only when di-methylatedat Lys79. The antibody does not cross-react with mono-methylated or tri-methylated Histone H3 Lys79 and other di-methylated sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% proclin300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
Histone H3
Gene ID
8290; 8350
Human swiss
Q16695; P68431
Protein Name
Histone H3 (Di Methyl Lys79)
Synonyms
H3t; H3. 4; H3/g; H3FT; H3C16; HIST3H3; DiMethyl-Histone H3-K79
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