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Primary Antibodies
Siglec-8 (AB4874) Rabbit mAb
Siglec-8 (AB4874) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2423
Species Reactivity:Human,Mouse,Rat
Application:WB,FC,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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Siglec-8 (AB4874) Rabbit mAb

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Product Details
Product Name
Siglec-8 (AB4874) Rabbit mAb
Description
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e. g. , CD33 (MIM 159590)) , are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13. 3-q13. 4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964) , and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al. , 2000 [PubMed 11095983]) .
Catalog No
M2423
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB4874
Isotype
IgG
Application
WB, FC, ELISA
Application Dilutions
WB, 1:1000-1:5000 | FC, 1:50-1:100 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 17 - 363 of human Siglec - 8.
Specificity
This antibody detects endogenous levels of Siglec-8 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% proclin300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
SIGLEC8
Gene ID
27181
Human swiss
Q9NYZ4
Protein Name
Siglec-8
Synonyms
SAF2; SIGLEC-8; SIGLEC8L; SIGLEC8; Siglec-8
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