25% Off Select Antibodies and ELISA Kits
Sign In/Register 0

We use cookies, check our Privacy Policies.

Caspase-1 p20 (AB2832) Rabbit mAb
Caspase-1 p20 (AB2832) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2292
Species Reactivity:Human
Application:WB,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
Product Details
Product Name
Caspase-1 p20 (AB2832) Rabbit mAb
Description
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.
Catalog No
M2292
Species Reactivity
Human
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB2832
Isotype
IgG
Application
WB, ELISA
Application Dilutions
WB, 1:2000-1:8000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 200 - 300 of human Caspase - 1 p20.
Specificity
This antibody detects endogenous levels of Caspase-1 p20 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.09% Sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
CASP1
Gene ID
834
Human swiss
P29466
Protein Name
Caspase-1 p20
Synonyms
ICE; P45; IL1BC; Caspase-1 p20
Related Products