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Primary Antibodies
eIF4EBP1 (Phospho Thr37/Thr46) (AB3383) Rabbit mAb
eIF4EBP1 (Phospho Thr37/Thr46) (AB3383) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2225
Species Reactivity:Rat
Application:WB,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
# Datasheet #
# SDS #
Recombinant Antibody
20 ul Size Available
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eIF4EBP1 (Phospho Thr37/Thr46) (AB3383) Rabbit mAb

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Product Details
Product Name
eIF4EBP1 (Phospho Thr37/Thr46) (AB3383) Rabbit mAb
Description
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) , which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Catalog No
M2225
Species Reactivity
Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Phospho T37/T46
Clone
AB3383
Isotype
IgG
Application
WB, ELISA
Application Dilutions
WB, 1:2000-1:8000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic phosphorylated peptide around T37&T46 of rat EIF4EBP1 protein.
Specificity
The antibody detects endogenous levels of eIF4EBP1 protein only when phosphorylated at Thr37/Thr46. The antibody does not cross-react with eIF4EBP1 phosphorylated at other sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.09% Sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
EIF4EBP1
Gene ID
1978
Human swiss
Q13541
Protein Name
eIF4EBP1 (Phospho Thr37/Thr46)
Synonyms
BP-1; 4EBP1; 4E-BP1; PHAS-I; Phospho-eIF4EBP1-T37/T46
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