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Primary Antibodies
TRβ1/THRB (AB5136) Rabbit mAb
TRβ1/THRB (AB5136) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2221
Species Reactivity:Human
Application:WB,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
# Datasheet #
# SDS #
Recombinant Antibody
20 ul Size Available
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TRβ1/THRB (AB5136) Rabbit mAb

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Product Details
Product Name
TRβ1/THRB (AB5136) Rabbit mAb
Description
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR) , a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4) , with normal or slightly elevated thyroid stimulating hormone (TSH) . Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.
Catalog No
M2221
Species Reactivity
Human
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB5136
Isotype
IgG
Application
WB, ELISA
Application Dilutions
WB, 1:1000-1:5000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1 - 91 of human TRβ1/THRB.
Specificity
This antibody detects endogenous levels of TRβ1/THRB protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.09% Sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
THRB
Gene ID
7068
Human swiss
P10828
Protein Name
TRβ1/THRB
Synonyms
TRb; GRTH; PRTH; THR1; ERBA2; NR1A2; THRB1; THRB2; TRbeta; THRbeta; TRbeta1; C-ERBA-2; THRbeta1; Thrbeta2; C-ERBA-BETA; TRβ1/THRB
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