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Primary Antibodies
HCoV-229E Spike S2 (AB3688) Rabbit mAb
HCoV-229E Spike S2 (AB3688) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2218
Species Reactivity:HCoV-229E
Application:WB,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
# Datasheet #
# SDS #
Recombinant Antibody
20 ul Size Available
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HCoV-229E Spike S2 (AB3688) Rabbit mAb

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Product Details
Product Name
HCoV-229E Spike S2 (AB3688) Rabbit mAb
Description
S1 region attaches the virion to the cell membrane by interacting with host ANPEP/aminopeptidase N, initiating the infection. Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide of S2 region and activating membranes fusion. S2 region belongs to the class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
Catalog No
M2218
Species Reactivity
HCoV-229E
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB3688
Isotype
IgG
Application
WB, ELISA
Application Dilutions
WB, 1:10000-1:80000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
This information is considered to be commercially sensitive.
Specificity
This antibody detects endogenous levels of HCoV-229E Spike S2 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% proclin300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
HCoV-229E Spike S2
Gene ID
918758
Human swiss
P15423
Protein Name
HCoV-229E Spike S2
Synonyms
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Primary Antibodies

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    • Research Areas

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