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Pseudouridine / 5-ribosyluracil (AB4657) Rabbit mAb
Pseudouridine / 5-ribosyluracil (AB4657) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2193
Species Reactivity:Species independent
Application:DB,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
Product Details
Product Name
Pseudouridine / 5-ribosyluracil (AB4657) Rabbit mAb
Description
Pseudouridine (Ψ) was among the first post-transcriptional modifications discovered and is overall one of the most abundant(1) . It is present in a wide range of cellular RNAs and is highly conserved across species. Ψ is derived from uridine (U) via base-specific isomerization catalyzed by Ψ synthases. The site-specific pseudouridylation goes through either snoRNA-dependent (requires H/ACA RNP) or-independent mechanism (requires pseudouridine synthase (PUS) family enzymes) (2) . It has an extra hydrogen-bond donor at its non-Watson-Crick edge. When incorporated into RNA, Ψ can alter RNA secondary structure by increasing base stacking, improving base pairing and rigidifying sugar-phosphate backbone5. The chemical and physical properties of RNA can be altered with the incorporation of Ψ, which could contribute to subsequent cellular functions.
Catalog No
M2193
Species Reactivity
Species independent
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB4657
Isotype
IgG
Application
DB, ELISA
Application Dilutions
DB, 1:1000-1:10000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
Chemical compounds corresponding to Pseudouridine / 5 - ribosyluracil / Y.
Specificity
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% proclin300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
Pseudouridine
Gene ID
CAS: 1445-07-4
Human swiss
Protein Name
Pseudouridine / 5-ribosyluracil
Synonyms
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