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XPD/ERCC2 (AB5253) Rabbit mAb
XPD/ERCC2 (AB5253) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M1731
Species Reactivity:Human,Mouse,Rat
Application:WB,IHC-P,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
Product Details
Product Name
XPD/ERCC2 (AB5253) Rabbit mAb
Description
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Catalog No
M1731
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB5253
Isotype
IgG
Application
WB, IHC-P, ELISA
Application Dilutions
WB, 1:500-1:1000 | IHC-P, 1:50-1:200 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 600 - 700 of human XPD/ERCC2.
Specificity
This antibody detects endogenous levels of XPD/ERCC2 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
ERCC2
Gene ID
2068
Human swiss
P18074
Protein Name
XPD/ERCC2
Synonyms
EM9; TTD; XPD; TTD1; COFS2; TFIIH; XPD/ERCC2
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