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Alpha-2-Macroglobulin (A2M) (AB2609) Rabbit mAb
Alpha-2-Macroglobulin (A2M) (AB2609) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M1340
Species Reactivity:Human,Mouse,Rat
Application:WB,IHC-P,IF/ICC,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
Product Details
Product Name
Alpha-2-Macroglobulin (A2M) (AB2609) Rabbit mAb
Description
The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified.
Catalog No
M1340
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB2609
Isotype
IgG
Application
WB, IHC-P, IF/ICC, ELISA
Application Dilutions
WB, 1:500-1:1000 | IHC-P, 1:200-1:2000 | IF/ICC, 1:100-1:400 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1200 - 1300 of human Alpha - 2 - Macroglobulin (A2M).
Specificity
This antibody detects endogenous levels of Alpha-2-Macroglobulin (A2M) protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
A2M
Gene ID
2
Human swiss
P01023
Protein Name
Alpha-2-Macroglobulin (A2M)
Synonyms
A2MD; CPAMD5; FWP007; S863-7; Alpha-2-Macroglobulin (A2M)
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