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SF3B3/SAP130 (AB4861) Rabbit mAb
SF3B3/SAP130 (AB4861) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M1298
Species Reactivity:Human,Mouse,Rat
Application:WB,IHC-P,IF/ICC,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
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SF3B3/SAP130 (AB4861) Rabbit mAb

Immunofluorescence analysis of U-2 OS cells using SF3B3/SAP130 Rabbit mAb (M1298) at dilution of 1:100 (40x lens).Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (SA1138) at 1:500 dilution.Blue: DAPI for nuclear staining.

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Product Details
Product Name
SF3B3/SAP130 (AB4861) Rabbit mAb
Description
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP) . The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II) 31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex) . These complexes may function in chromatin modification, transcription, splicing, and DNA repair.
Catalog No
M1298
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB4861
Isotype
IgG
Application
WB, IHC-P, IF/ICC, ELISA
Application Dilutions
WB, 1:500-1:2000 | IHC-P, 1:50-1:200 | IF/ICC, 1:50-1:200 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1101 - 1217 of human SF3B3/SAP130 (Q15393).
Specificity
This antibody detects endogenous levels of SF3B3/SAP130 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
SF3B3
Gene ID
23450
Human swiss
Q15393
Protein Name
SF3B3/SAP130
Synonyms
RSE1; SAP130; SF3b130; STAF130; SF3B3/SAP130
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Price/Quantity:
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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