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Primary Antibodies
RPE65 (AB4790) Rabbit mAb
RPE65 (AB4790) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M1293
Species Reactivity:Mouse,Rat
Application:WB,IHC-P,IF/ICC,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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RPE65 (AB4790) Rabbit mAb

Immunofluorescence analysis of paraffin-embedded rat eye using RPE65 Rabbit mAb (M1293) at dilution of 1:100 (40x lens).Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (SA1138) at 1:500 dilution.Blue: DAPI for nuclear staining.

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Product Details
Product Name
RPE65 (AB4790) Rabbit mAb
Description
The protein encoded by this gene is a component of the vitamin A visual cycle of the retina which supplies the 11-cis retinal chromophore of the photoreceptors opsin visual pigments. It is a member of the carotenoid cleavage oxygenase superfamily. All members of this superfamily are non-heme iron oxygenases with a seven-bladed propeller fold and oxidatively cleave carotenoid carbon:carbon double bonds. However, the protein encoded by this gene has acquired a divergent function that involves the concerted O-alkyl ester cleavage of its all-trans retinyl ester substrate and all-trans to 11-cis double bond isomerization of the retinyl moiety. As such, it performs the essential enzymatic isomerization step in the synthesis of 11-cis retinal. Mutations in this gene are associated with early-onset severe blinding disorders such as Leber congenital.
Catalog No
M1293
Species Reactivity
Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB4790
Isotype
IgG
Application
WB, IHC-P, IF/ICC, ELISA
Application Dilutions
WB, 1:500-1:1000 | IHC-P, 1:100-1:1000 | IF/ICC, 1:100-1:1000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 400 - 500 of human RPE65 (Q16518).
Specificity
This antibody detects endogenous levels of RPE65 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
RPE65
Gene ID
6121
Human swiss
Q16518
Protein Name
RPE65
Synonyms
p63; BCO3; LCA2; RP20; rd12; mRPE65; sRPE65; RPE65
Related Products

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HRP* Goat Anti Mouse IgG(H+L)

Price/Quantity:
$50

Size:
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Catalog No: SA0002

HRP* Goat Anti Rabbit IgG(H+L)

Price/Quantity:
$50

Size:
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Primary Antibodies

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