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Rac1/Cdc42(Phospho Ser71) (AB4708) Rabbit mAb
Rac1/Cdc42(Phospho Ser71) (AB4708) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M1228
Species Reactivity:Human
Application:WB,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
Product Details
Product Name
Rac1/Cdc42(Phospho Ser71) (AB4708) Rabbit mAb
Description
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP) , which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]
Catalog No
M1228
Species Reactivity
Human
Clonality
Monoclonal
Host
Rabbit
Modifcation
Phospho S71
Clone
AB4708
Isotype
IgG
Application
WB, ELISA
Application Dilutions
WB, 1:500-1:2000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic phosphorylated peptide around S71 of human Rac1/Cdc42CDC42.
Specificity
The antibody detects endogenous levels of Rac1/Cdc42 protein only when phosphorylated at Ser71. The antibody does not cross-react with Rac1/Cdc42 phosphorylated at other sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
CDC42/RAC1
Gene ID
998; 5879
Human swiss
P60953; P63000
Protein Name
Rac1/Cdc42(Phospho Ser71)
Synonyms
CDC42Hs; G25K; TKS; Phospho-Rac1/Cdc42-S71
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