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Primary Antibodies
ACTN2 (AB2539) Rabbit mAb
ACTN2 (AB2539) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M1090
Species Reactivity:Human,Mouse,Rat
Application:WB,IF/ICC,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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ACTN2 (AB2539) Rabbit mAb

Confocal imaging of paraffin-embedded Mouse heart using ACTN2 Rabbit mAb (M1090, dilution 1:200) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (SA1138, dilution 1:500) (Red).DAPI was used for nuclear staining (Blue).Objective: 40x.Perform high pressure antigen retrieval with 0.01 M citRate buffer (pH 6.0) prior to IF staining.

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Product Details
Product Name
ACTN2 (AB2539) Rabbit mAb
Description
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
Catalog No
M1090
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB2539
Isotype
IgG
Application
WB, IF/ICC, ELISA
Application Dilutions
WB, 1:3000-1:18000 | IF/ICC, 1:200-1:800 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1 - 100 of human ACTN2.
Specificity
This antibody detects endogenous levels of ACTN2 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
ACTN2
Gene ID
88
Human swiss
P35609
Protein Name
ACTN2
Synonyms
MPD6; CMH23; CMYP8; CMD1AA; MYOCOZ; ACTN2
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Primary Antibodies

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