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Primary Antibodies
UPF1/RENT1 (AB5179) Rabbit mAb
UPF1/RENT1 (AB5179) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M1040
Species Reactivity:Human,Mouse,Rat
Application:WB,IF/ICC,IP,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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UPF1/RENT1 (AB5179) Rabbit mAb

Confocal imaging of C6 cells using UPF1/RENT1 Rabbit mAb (M1040, dilution 1:100) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (SA1138, dilution 1:500) (Red).The cells were counterstained with α-Tubulin Mouse mAb (W0051, dilution 1:400) followed by incubation with 488-conjugated Goat anti-Mouse IgG (H+L) (SA0662, dilution 1:500) (Green).DAPI was used for nuclear staining (Blue).Objective: 100x.

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Product Details
Product Name
UPF1/RENT1 (AB5179) Rabbit mAb
Description
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD) . When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.
Catalog No
M1040
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB5179
Isotype
IgG
Application
WB, IF/ICC, IP, ELISA
Application Dilutions
WB, 1:1000-1:6000 | IF/ICC, 1:50-1:200 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1 - 100 of human UPF1/RENT1 (Q92900).
Specificity
This antibody detects endogenous levels of UPF1/RENT1 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
UPF1
Gene ID
5976
Human swiss
Q92900
Protein Name
UPF1/RENT1
Synonyms
UTF; HUPF1; NORF1; RENT1; smg-2; pNORF1; UPF1/RENT1
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Primary Antibodies

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    • Research Areas

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