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Primary Antibodies
MBNL1 (AB4136) Rabbit mAb
MBNL1 (AB4136) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0993
Species Reactivity:Human
Application:WB,IF/ICC,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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MBNL1 (AB4136) Rabbit mAb

Confocal imaging of U-2 OS cells using MBNL1 Rabbit mAb (M0993, dilution 1:100) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (SA1138, dilution 1:500) (Red).The cells were counterstained with α-Tubulin Mouse mAb (W0051, dilution 1:400) followed by incubation with 488-conjugated Goat anti-Mouse IgG (H+L) (SA0662, dilution 1:500) (Green).DAPI was used for nuclear staining (Blue).Objective: 100x.

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Product Details
Product Name
MBNL1 (AB4136) Rabbit mAb
Description
This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.
Catalog No
M0993
Species Reactivity
Human
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB4136
Isotype
IgG
Application
WB, IF/ICC, ELISA
Application Dilutions
WB, 1:500-1:2000 | IF/ICC, 1:50-1:200 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 289 - 388 of human MBNL1 (Q9NR56).
Specificity
This antibody detects endogenous levels of MBNL1 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
MBNL1
Gene ID
4154
Human swiss
Q9NR56
Protein Name
MBNL1
Synonyms
EXP; MBNL; MBNL1
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Primary Antibodies

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