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Primary Antibodies
KRAS+HRAS+NRAS (AB4037) Rabbit mAb
KRAS+HRAS+NRAS (AB4037) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0947
Species Reactivity:Human,Mouse,Rat
Application:WB,IF/ICC,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
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KRAS+HRAS+NRAS (AB4037) Rabbit mAb

Confocal imaging of U-2 OS cells using KRAS+HRAS+NRAS Rabbit mAb (M0947, dilution 1:100) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (SA1138, dilution 1:500) (Red).The cells were counterstained with α-Tubulin Mouse mAb (W0051, dilution 1:400) followed by incubation with 488-conjugated Goat anti-Mouse IgG (H+L) (SA0662, dilution 1:500) (Green).DAPI was used for nuclear staining (Blue).Objective: 100x.

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Product Details
Product Name
KRAS+HRAS+NRAS (AB4037) Rabbit mAb
Description
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Catalog No
M0947
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB4037
Isotype
IgG
Application
WB, IF/ICC, ELISA
Application Dilutions
WB, 1:500-1:1000 | IF/ICC, 1:50-1:200 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1 - 100 of human NRAS.
Specificity
This antibody detects endogenous levels of KRAS+HRAS+NRAS protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
NRAS
Gene ID
4893; 3265; 3845
Human swiss
P01111; P01112; P01116_
Protein Name
KRAS+HRAS+NRAS
Synonyms
NS6; CMNS; KRAS; NCMS; ALPS4; N-ras; NRAS1; KRAS+HRAS+NRAS
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Primary Antibodies

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    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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