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Primary Antibodies
MRE11 (AB4222) Rabbit mAb
MRE11 (AB4222) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0831
Species Reactivity:Human,Mouse
Application:WB,ELISA,ChIP
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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MRE11 (AB4222) Rabbit mAb

Chromatin immunoprecipitation analysis of extracts of LNCaP cells, using Mre11 antibody (M0831) and rabbit IgG.The amount of immunoprecipitated DNA was checked by quantitative PCR.Histogram was constructed by the ratios of the immunoprecipitated DNA to the input.

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Product Details
Product Name
MRE11 (AB4222) Rabbit mAb
Description
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Catalog No
M0831
Species Reactivity
Human, Mouse
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB4222
Isotype
IgG
Application
WB, ELISA, ChIP
Application Dilutions
WB, 1:500-1:2000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. | ChIP, 5μg antibody for 10μg-15μg of Chromatin
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 400 - 500 of human MRE11.
Specificity
This antibody detects endogenous levels of MRE11 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
MRE11
Gene ID
4361
Human swiss
P49959
Protein Name
MRE11
Synonyms
ATLD; HNGS1; MRE11A; MRE11B; MRE11
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Primary Antibodies

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