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Primary Antibodies
tPA/PLAT (AB5099) Rabbit mAb
tPA/PLAT (AB5099) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0828
Species Reactivity:Human,Mouse,Rat
Application:WB,IF/ICC,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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tPA/PLAT (AB5099) Rabbit mAb

Confocal imaging of human placenta using tPA/PLAT Rabbit mAb (M0828, at dilution of 1:100) (Red).DAPI was used for nuclear staining (blue).Objective: 40x.Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IF staining protocol.

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Product Details
Product Name
tPA/PLAT (AB5099) Rabbit mAb
Description
This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Catalog No
M0828
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB5099
Isotype
IgG
Application
WB, IF/ICC, ELISA
Application Dilutions
WB, 1:1000-1:6000 | IF/ICC, 1:100-1:400 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 463 - 562 of human tPA/tPA/PLAT.
Specificity
This antibody detects endogenous levels of tPA/PLAT protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
PLAT
Gene ID
5327
Human swiss
P00750
Protein Name
tPA/PLAT
Synonyms
TPA; T-PA; tPA/PLAT
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