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PABPN1 (AB4442) Rabbit mAb
PABPN1 (AB4442) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0703
Species Reactivity:Human,Mouse,Rat
Application:WB,IHC-P,IF/ICC,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
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PABPN1 (AB4442) Rabbit mAb

Confocal imaging of C2C12 cells using PABPN1 Rabbit mAb (M0703, dilution 1:200) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (SA1138, dilution 1:500) (Red).The cells were counterstained with α-Tubulin Mouse mAb (W0051, dilution 1:400) followed by incubation with 488-conjugated Goat anti-Mouse IgG (H+L) (SA0662, dilution 1:500) (Green).DAPI was used for nuclear staining (Blue).Objective: 100x.

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Product Details
Product Name
PABPN1 (AB4442) Rabbit mAb
Description
This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.
Catalog No
M0703
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB4442
Isotype
IgG
Application
WB, IHC-P, IF/ICC, ELISA
Application Dilutions
WB, 1:1000-1:6000 | IHC-P, 1:200-1:2000 | IF/ICC, 1:200-1:2000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1 - 100 of human PABPN1 (Q86U42).
Specificity
This antibody detects endogenous levels of PABPN1 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
PABPN1
Gene ID
8106
Human swiss
Q86U42
Protein Name
PABPN1
Synonyms
OPMD; PAB2; PABII; PABP2; PABP-2; PABPN1
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Primary Antibodies

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