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Primary Antibodies
Ku80 (AB4041) Rabbit mAb
Ku80 (AB4041) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0689
Species Reactivity:Human
Application:WB,IHC-P,IF/ICC,IP,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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Ku80 (AB4041) Rabbit mAb

Confocal imaging of HeLa cells using Ku80 Rabbit mAb (M0689, dilution 1:100) (Red).The cells were counterstained with α-Tubulin Mouse mAb (W0051, dilution 1:400) (Green).DAPI was used for nuclear staining (blue).Objective: 60x.

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Product Details
Product Name
Ku80 (AB4041) Rabbit mAb
Description
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D) J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D) J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Catalog No
M0689
Species Reactivity
Human
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB4041
Isotype
IgG
Application
WB, IHC-P, IF/ICC, IP, ELISA
Application Dilutions
WB, 1:1000-1:6000 | IHC-P, 1:200-1:800 | IF/ICC, 1:100-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 633 - 732 of human Ku80.
Specificity
This antibody detects endogenous levels of Ku80 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
XRCC5
Gene ID
7520
Human swiss
P13010
Protein Name
Ku80
Synonyms
KU80; KUB2; Ku86; NFIV; KARP1; KARP-1; Ku80
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Primary Antibodies

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    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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