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SERCA2/ATP2A2 (AB4850) Rabbit mAb
SERCA2/ATP2A2 (AB4850) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0676
Species Reactivity:Human,Mouse,Rat
Application:WB,IF/ICC,IP,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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SERCA2/ATP2A2 (AB4850) Rabbit mAb

Confocal imaging of Hep G2 cells using SERCA2/ATP2A2 Rabbit mAb (M0676, dilution 1:100) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (SA1138, dilution 1:500) (Red).The cells were counterstained with α-Tubulin Mouse mAb (W0051, dilution 1:400) followed by incubation with 488-conjugated Goat anti-Mouse IgG (H+L) (SA0662, dilution 1:500) (Green).DAPI was used for nuclear staining (Blue).Objective: 100x.

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Product Details
Product Name
SERCA2/ATP2A2 (AB4850) Rabbit mAb
Description
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of the skeletal muscle. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Other types of mutations in this gene have been associated with various forms of muscular dystrophies. Alternative splicing results in multiple transcript variants encoding different isoforms.
Catalog No
M0676
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB4850
Isotype
IgG
Application
WB, IF/ICC, IP, ELISA
Application Dilutions
WB, 1:1000-1:6000 | IF/ICC, 1:100-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 943 - 1042 of human SERCA2/ATP2A2.
Specificity
This antibody detects endogenous levels of SERCA2/ATP2A2 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
ATP2A2
Gene ID
488
Human swiss
P16615
Protein Name
SERCA2/ATP2A2
Synonyms
DD; DAR; ATP2B; SERCA2; SERCA2/ATP2A2
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