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Primary Antibodies
Fibrillarin/U3 RNP (AB3499) Rabbit mAb
Fibrillarin/U3 RNP (AB3499) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0576
Species Reactivity:Human,Mouse,Rat
Application:WB,IF/ICC,IP,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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Fibrillarin/U3 RNP (AB3499) Rabbit mAb

Confocal imaging of U-2OS cells using Fibrillarin/U3 RNP Rabbit mAb (M0576, dilution 1:100) (Red).The cells were counterstained with α-Tubulin Mouse mAb (W0051, dilution 1:400) (Green).DAPI was used for nuclear staining (blue).Objective: 60x.

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Product Details
Product Name
Fibrillarin/U3 RNP (AB3499) Rabbit mAb
Description
This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.
Catalog No
M0576
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB3499
Isotype
IgG
Application
WB, IF/ICC, IP, ELISA
Application Dilutions
WB, 1:1000-1:10000 | IF/ICC, 1:100-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 222 - 321 of human Fibrillarin/U3 RNP.
Specificity
This antibody detects endogenous levels of Fibrillarin/U3 RNP protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
FBL
Gene ID
2091
Human swiss
P22087
Protein Name
Fibrillarin/U3 RNP
Synonyms
FIB; FLRN; Nop1; RNU3IP1; Fibrillarin/U3 RNP
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Primary Antibodies

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