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CDKN1B/p27KIP1 (AB3049) Rabbit mAb
CDKN1B/p27KIP1 (AB3049) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0551
Species Reactivity:Human,Mouse,Rat
Application:WB,IHC-P,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
Product Details
Product Name
CDKN1B/p27KIP1 (AB3049) Rabbit mAb
Description
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4) .
Catalog No
M0551
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB3049
Isotype
IgG
Application
WB, IHC-P, ELISA
Application Dilutions
WB, 1:1000-1:2000 | IHC-P, 1:200-1:800 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 99 - 198 of human CDKN1B/p27KIP1.
Specificity
This antibody detects endogenous levels of CDKN1B/p27KIP1 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
CDKN1B
Gene ID
1027
Human swiss
P46527
Protein Name
CDKN1B/p27KIP1
Synonyms
KIP1; MEN4; CDKN4; MEN1B; P27KIP1; CDKN1B/p27KIP1
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